Cruise 47 miles east on Interstate 70 from Greenville to Effingham, Illinois. This relaxed stretch passes through Vandalia’s historic district and rural farmland, offering travelers a peaceful glimpse of Midwestern life.

The Midwest is the crossroads of America—a region where long, open highways meet friendly towns, rolling farmland, and Great Lakes shorelines. Covering Iowa, Missouri, Illinois, Indiana, Ohio, Minnesota, Wisconsin, and Michigan, the Midwest offers a rich blend of rural charm, industrial heritage, and natural beauty. Whether you’re navigating the wide cornfields of Iowa or hugging the rocky shores of Lake Superior, the region’s roads are built for exploration.
This is where iconic byways like Historic Route 66 and the Great River Road converge with scenic loops around glacial lakes and wooded hills. In places like southern Missouri and northern Wisconsin, the terrain becomes unexpectedly dramatic—filled with bluffs, rivers, and forested stretches. Meanwhile, cities like Chicago, Minneapolis, St. Louis, and Cleveland serve as vibrant urban hubs offering cultural detours, architectural wonders, and food scenes worth the stop.
From Michigan’s winding coastal routes and ferry-linked peninsulas to Ohio’s Amish country and Indiana’s covered bridge trails, the Midwest is full of surprises. It’s a region best experienced slowly, with the windows down and a cooler in the backseat. These are the roads that define the heartland—and they’re ready for your next great American drive.

Cruise 47 miles east on Interstate 70 from Greenville to Effingham, Illinois. This relaxed stretch passes through Vandalia’s historic district and rural farmland, offering travelers a peaceful glimpse of Midwestern life.

Take a short but scenic ride along Missouri Supplemental Highway H from Noel to Pineville. Follow Kings Highway through the wooded Elk River valley and connect to I-49 for more Ozark exploration.

Cruise 71 miles east along Interstate 44 from Joplin to Springfield, Missouri. Enjoy scenic Ozarks landscapes, small-town stops, and a dash of Route 66 history on this classic southwest Missouri highway drive.

Cruise 11 scenic miles along Missouri Highway 90 from Southwest City to Noel. This winding Ozark drive passes through quiet forests, rolling farmland, and the charming riverside town of Noel — perfect for a quick day trip or a weekend float.

Take a short but scenic drive along Missouri Supplemental Route P, from Route 86 west of Eagle Rock to the Arkansas state line. This quiet connector marks the beginning of the legendary Arkansas Highway 23, known for its winding path through the Ozarks and the Pig Trail…

Explore the 9-mile stretch of Missouri State Route 86 from Carr Lane to Eagle Rock. This scenic Ozark drive near the Arkansas border winds through forest, farmland, and the recreational hub of Golden, Missouri.

Travel 13 miles along Missouri Route 39 from Shell Knob to Carr Lane, featuring a scenic Table Rock Lake crossing, wooded Ozark landscapes, and a peaceful drive through rural Barry County.

Explore a short but scenic 4-mile drive along Taney County Highway 165 in Hollister, Missouri. From U.S. 65 Business to MO-265, this route offers wooded views, residential curves, and the popular Branson Scenic Overlook.

Take a scenic 4-mile drive through Hollister, Missouri along U.S. Highway 65 Business. This former alignment of US-65 winds past Lake Taneycomo, through Hollister’s Tudor-style downtown, and reconnects with Highway 165 west of town.

Explore 12 miles of Missouri Route 76 from Forsyth to Hollister, including scenic views, wooded hills, and access to Lake Taneycomo. This route blends quiet Ozark towns with growing Branson suburbs.

Cruise 20 miles through the scenic Ozark hills on U.S. Highway 160 from Rueter to Forsyth, Missouri. This winding stretch cuts through forested ridges, small communities, and ends at a modern roundabout near Bull Shoals Lake.

Explore Missouri Route 125 from the Arkansas border to Rueter—a 10-mile scenic drive through the quiet forests and farmland of the Ozarks. Discover small towns, peaceful curves, and a tranquil rural atmosphere along the way.