Discover the history, route map, and travel highlights of U.S. Route 27—a north–south highway running from Miami, Florida to Fort Wayne, Indiana. Explore key cities, scenic byways, and regional connections.
U.S. Route 27 (US 27) is a major north–south U.S. Highway that spans approximately 1,373 miles from the tropical climate of South Florida to the rolling hills of Fort Wayne, Indiana. Serving as a key corridor through the southeastern United States, US 27 traverses six states: Florida, Georgia, Tennessee, Kentucky, Ohio, and Indiana. The route links rural regions with growing metro areas, supporting both regional travel and economic development.
In Florida, US 27 begins in the city of Miami and stretches northwest through Lake Okeechobee, central Florida’s citrus belt, and cities like Sebring, Ocala, and Tallahassee. Upon entering Georgia, it follows the western part of the state, paralleling the Alabama border through communities such as Columbus, LaGrange, and Rome. In Tennessee, it runs through Chattanooga, where it briefly joins the freeway system before continuing into the scenic terrain of Kentucky.
In the Bluegrass State, US 27 passes through Lexington and into northern Kentucky before crossing the Ohio River into Cincinnati. From there, the route continues north into Indiana, where it serves smaller towns and eventually terminates in Fort Wayne. Along its route, US 27 intersects with multiple interstates and U.S. highways, providing crucial connectivity across rural and urban landscapes.
Drive southbound on U.S. Highway 27 through Chattanooga, Tennessee, crossing the Tennessee River and passing iconic downtown landmarks before connecting with Interstate 24. A short, scenic urban route showcasing the best of the city’s riverfront and skyline.
Drive 4 miles north along U.S. Highway 27 from downtown Chattanooga to Red Bank, Tennessee. This short but busy stretch crosses the Tennessee River and links urban Chattanooga with its scenic northern suburbs.